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Surak's avatar

Reading the magnificent meta-analysis of COVID treatments here: https://c19early.org/

Conclusions: IVM is the most effective at reducing mortality when taken prophylactically; HCQ is the most effective at reducing mortality when taken during early treatment. Interesting how that works out.

My metric for defining effectiveness is to maximize the minimum improvement in the confidence interval. IVM reduces mortality at least 50% when taken prophylactically; HCQ reduces mortality at least 61% when taken during early treatment.

https://c19early.org/#fpdpreppep

https://c19early.org/#fpdearly

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Eleftherios Gkioulekas's avatar

There is always some uncertainty in these numbers so not sure how meaningful comparisons are. Personally I would be inclined to cycle between HCQ and ivm prophylactic use say every 5 years, and for someone who is very high risk, they could use both. Ivermectin is very good at resolving and preventing the oxygen desaturation resulting from microscopic bloodclots. Currently I am taking one half of what I need for prophylaxis because I already have some natural immunity. For more prophylaxis, one can do the nasal washes with a xylitol spray, which improves the microbiome up in the nose, as advocated by Dr. McCullough.

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